A primary malignant melanoma will most likely metastasize to which organ?

Prepare for the NBEO Histology Exam with comprehensive quizzes and practice questions. Study with flashcards and detailed explanations to ensure you're ready for the test day. Improve your histology knowledge efficiently!

Multiple Choice

A primary malignant melanoma will most likely metastasize to which organ?

Explanation:
Melanoma commonly spreads through the bloodstream to distant organs, and among visceral sites the liver is the most frequent target. The liver’s rich blood supply and its network of sinusoids readily trap circulating melanoma cells, allowing them to lodge, colonize, and grow there. While brain and lungs can also harbor metastases, and metastasis to the heart is relatively rare, the liver most often becomes the first and most common site of distant spread for a primary melanoma.

Melanoma commonly spreads through the bloodstream to distant organs, and among visceral sites the liver is the most frequent target. The liver’s rich blood supply and its network of sinusoids readily trap circulating melanoma cells, allowing them to lodge, colonize, and grow there. While brain and lungs can also harbor metastases, and metastasis to the heart is relatively rare, the liver most often becomes the first and most common site of distant spread for a primary melanoma.

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